Bilateral Sequential Optic Neuritis in Behçet's Syndrome

Dear Editor, Optic neuritis is the most common inflammatory optic neuropathy affecting young adults [1]. Less commonly, optic neuritis may be associated with systemic autoimmune disease, of which Behçet’s syndrome is an extremely rare cause, with only 20 identified cases to date [2]. To the best of our knowledge, there have been no reports in Korean patients. Herein, we report a patient presenting with bilateral sequential optic neuritis who was finally diagnosed with Behçet’s syndrome. A 30-year-old man visited the outpatient clinic for headache, periocular pain, and scotoma in his left eye. The symptom had developed over a period of several hours. He had no remarkable medical history, except experience of similar symptoms in his right eye about one year prior. Brain magnetic resonance imaging, cerebrospinal f luid tapping, and all markers for infectious diseases showed normal results. On ophthalmologic examination, his best corrected visual acuity was 20 / 20 in both eyes, and the anterior segments were normal in both eyes. Small central scotoma was noticed from Goldmann perimetry in both eyes. The left disc was swollen (Fig. 1A), and a small pigment epithelial detachment was found in his left eye on Korean J Ophthalmol 2015;29(2):140-141 http://dx.doi.org/10.3341/kjo.2015.29.2.140